Now showing items 1-14 of 14

    • Balcells, María Elvira; Rojas, Luis; Le Corre, Nicole; Martínez Valdebenito, Constanza; Ceballos, María Elena; Ferrés, Marcela; Chang, Mayling; Vizcaya, Cecilia; Mondaca, Sebastián; Huete, Álvaro; Castro, Ricardo; Sarmiento, Mauricio; Villarroel, Luis; Pizarro, Alejandra; Ross, Patricio; Santander, Jaime; Lara, Bárbara; Ferrada, Marcela; Vargas Salas, Sergio Sebastián; Beltrán Pavez, Carolina Alejandra; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés; Caglevic, Christian; Mahave, Mauricio; Selman, Carolina; Gazitua, Raimundo; Briones, José Luis; Villarroel Espíndola, Franz; Balmaceda, Carlos; Espinoza, Manuel A.; Pereira, Jaime; Nervi, Bruno (Public Library Science, 2021)
      Background Convalescent plasma (CP), despite limited evidence on its efficacy, is being widely used as a compassionate therapy for hospitalized patients with COVID-19. We aimed to evaluate the efficacy and safety of ...
    • Aguilera Cortés, Paulina Andrea (Universidad de Chile., 2021)
      Durante las etapas tardías del ciclo replicativo, el ARN genómico (ARNg) del Virus de la Inmunodeficiencia Humana de tipo 1 (VIH-1) se ensambla en complejos ribonucleoprotéicos (mRNPs) específicos cuya composición determina ...
    • Pereira Montecinos, Camila Andrea (Universidad de Chile, 2020)
      El virus de la inmunodeficiencia humana tipo-1 (VIH-1) es el principal agente causal del síndrome de la inmunodeficiencia adquirida (SIDA). Su genoma corresponde a una molécula de ARN de simple hebra con polaridad positiva ...
    • Beltrán Pavez, Carolina Alejandra; Riquelme Barrios, Sebastian Andres; Oyarzún Arrau, Aarón; Gaete Argel, Aracelly Janis; González Stegmaier, Roxana; Cereceda Solis, Karina; Aguirre, Adam; Travisany Flores, Dante Felipe; Palma Vejares, Ricardo Fernando; Barriga Pinto, Gonzalo Andrés; Gaggero Brillouet, Aldo Andres; Martínez Valdebenito, Constanza; Le Corre, Nicole; Ferres Garrido, Marcela Viviana; Balcells, María Elvira; Fernández, Jorge; Ramírez, Eugenio; Villarroel, Franz; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo Andrés (American Association for the Advancement of Science, 2021)
      Chile has one of the worst numbers worldwide in terms of SARS-CoV-2 positive cases and COVID-19-related deaths per million inhabitants; thus, characterization of neutralizing antibody (NAb) responses in the general population ...
    • Figueroa, Fabián; Vega Gibson, Alonso Gonzalo; Catrileo, Joseline; Gaete Argel, Aracelly Janis; Riquelme Barrios, Sebastián Andrés; Alonso Palomares, Luis Antonio; Tapia Faúndes, Lorena; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo Andrés; Acevedo Acevedo, Mónica Loreto (Frontiers Media, 2021)
      N 6 -methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV). Here, we evaluated the impact of m6A writers, ...
    • Wolff Reyes, Marcelo José; Acevedo Acevedo, Mónica Loreto; Núñez, María Antonieta; Lafourcade, Mónica; Gaete Argel, Aracelly Janis; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Oxford University Press, 2022)
      We report neutralizing antibody titers (NAbTs) elicited by CoronaVac and BNT162b2 vaccines in healthcare workers with and without prior SARS-CoV-2 infection using both a pseudotype-based assay and a commercial kit. NAbTs ...
    • Peña, Mónica; Ampuero Martínez, Manuel Andrés; Garcés, Carlos; Gaggero Brillouet, Aldo Andres; García, Patricia; Velásquez, María Soledad; Luza, Ricardo; Álvarez, Pía; Paredes, Fabio; Acevedo, Johanna; Farfán Urzúa, Mauricio Javier; Solari, Sandra; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Elsevier, 2021)
      Screening, testing and contact tracing plays a pivotal role in control of the COVID-19 pandemic. To enable this it is necessary to increase the testing capacity. This study compared a SARS-CoV-2 rapid antigen test (RAT) ...
    • Rojas Araya, Bárbara Valeria (Universidad de Chile, 2023)
      Durante la infección causada por el virus de la inmunodeficiencia humana del tipo 1 (VIH-1), el ADN proviral es integrado en el genoma celular y luego la ARN polimerasa II sintetiza un único transcrito de 9-kb denominado ...
    • Soto, Abel A.; Ortiz, Gerardo; Contreras, Sofía; Soto Rifo, Ricardo Andrés; González, Pablo A. (MDPI, 2022)
      Herpesviruses are double-stranded DNA viruses occurring at a high prevalence in the human population and are responsible for a wide array of clinical manifestations and diseases, from mild to severe. These viruses are ...
    • Vargas, Leonardo; Valdivieso Berríos, Nicolás Alejandro; Tempio, Fabián; Simon Zegers, María Valeska; Sauma Mahaluf, Daniela Macarena; Valenzuela Pérez, Lucía Teresita; Beltrán Muñoz, Caroll Jenny; Castillo Delgado, Loriana Cecilia; Contreras Benavides, Ximena Stella; Acevedo Acevedo, Mónica Loreto; Acevedo, Johanna; González, Rafael I.; Valiente Echeverría, Fernando Andres; Soto Rifo, Ricardo Andrés; Rosemblatt Silber, Mario César; López Nitsche, Mercedes Natalia; Osorio Olivares, Fabiola Beatriz; Bono Merino, María Rosa (BMC, 2022)
      Background Chile was severely affected by COVID19 outbreaks but was also one of the first countries to start a nationwide program to vaccinate against the disease. Furthermore, Chile became one of the fastest countries to ...
    • Aguayo Abarca, Felipe Ignacio (Universidad de Chile, 2023)
      La depresión mayor es una enfermedad mental que afecta aproximadamente a 5% de la población mundial. En Chile la cifra asciende a un 6.2%, sin embargo, se observa que la prevalencia es aproximadamente 5 veces mayor en ...
    • Alonso-Palomares, Luis A.; Cáceres, C. Joaquín; Tapia, Rodrigo; Aguilera Cortés, Paulina Andrea; Valenzuela, Santiago; Valiente Echeverría, Fernando; Soto Rifo, Ricardo Andrés; Gaggero Brillouet, Aldo Andrés; Barriga Pinto, Gonzalo Andrés (Wiley, 2021)
    • Gaete Argel, Aracelly Janis; Velásquez, Felipe; Márquez Badilla, Chantal Loretto; Rojas Araya, Bárbara; Bueno Nieto, Constanza Francisca; Marín Rojas, Josefina; Cuevas Zúñiga, Miguel; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Frontiers Media, 2021)
      Tellurium oxyanion, tellurite (TeO3-2), is a highly toxic compound for many organisms. Its presence in the environment has increased over the past years due to industrial manufacturing processes and has been associated ...
    • Rojas, Masyelly; Luz Crawford, Patricia; Soto Rifo, Ricardo Andrés; Reyes Cerpa, Sebastián; Toro Ascuy, Daniela (MDPI, 2021)
      A key characteristic of Human immunodeficiency virus type 1 (HIV-1) infection is the generation of latent viral reservoirs, which have been associated with chronic immune activation and sustained inflammation. Macrophages ...